The Situation of Antibiotic Resistance in Klebsiella Pneumoniae and Carbapenemase-Producing Klebsiella Pneumoniae in Vietnam: A Cross-Sectional Study

Objective: Klebsiella pneumoniae (K. pneumoniae) is one of the most prevalent human pathogens. Carbapenemaseproducing klebsiella (CPKP) has recently developed significant antibiotic resistance, not just to carbapenem antibiotics but also majority other currently available antibiotics. Prior this point, there have been few international studies or publications on situation CPKP in Vietnam. Hence, study was conducted determine resistance K. and strains Can Tho, Material Methods: In total, 345 were isolated. Antibiotic susceptibility assessed via an automated microbiological system. A modified inactivation assay applied identify strains, followed by use MASTDISCS combi Carba plus disc system classify certain carbapenemases. Results: Of 110 represented isolation rate 31.9%. There a correlation (p-value<0.05) between specimen type, hospital unit ratio. All examined exhibited complete penicillin cefazolin. The significantly more resistant PTZ, cefepime, ciprofloxacin imipenem than non-CPKP (p-value<0.05). Amikacin, gentamicin TMP/SMX shown be effective treating patients infected with strains. Conclusion: accounts for 31.9% all infections. highest levels ampicillin, cefazoline, ciprofloxacin, ceftriaxone ceftazidime. TMP/ SMX least tested.